What is metabolic engineering?
The rational redesign – typically using genetic engineering – of organisms to meet commercial objectives, by the modification of existing – or the introduction of entirely new – metabolic pathways (Stephanopoulos 1999)
Introduction of specific modifications to metabolic networks for the purpose of improving cellular properties (Cortassa S et al. 2002)
Cortassa S, Aon M.A, Iglesias A.A, Lloyd D. 2002. An Introduction to Metabolic and Cellular Engineering. Singapore: World Scientific. p 1-34.
Stephanopoulos G. 1999. Metabolic Fluxes and Metabolic Engineering. Metabolic Engineering 1(1):1-11.