The stoichiometry of microbial cell growth

Growth of microorganisms consists of thousands of reaction, both catabolisms and anabolisms. However, according to the black box growth model and using the mass and charge balance, the cell growth can be modelled as a single reaction, for example:


  This reaction is based on the following assumptions:

  1. Glucose as a sole carbon and energy source
  2. Ammonium as a sole nitrogen source
  3. Cell growth yield is 0.5 g biomass/g glucose (based on experimental result)
  4. A typical biomass elemental composition is used where sulfur, phosphate dan trace elements are negligible
  5. Aerobic growth in which only produce biomass, carbon dioxide, water, and hydrogen

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